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中华胸部外科电子杂志 ›› 2021, Vol. 08 ›› Issue (04) : 205 -208. doi: 10.3877/cma.j.issn.2095-8773.2021.04.01

国际胸外科专栏

Non-intubated minimally-invasive lung surgery in Germany-current status and outlook
Patrick Zardo1,(), Norman Zinne1, Alaa Selman1, Hayan Merhej1, Tobias Goecke1, Henning Starke2, Daniel Jaeger2, Jan Karsten2, Axel Haverich1   
  1. 1. Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    2. Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
  • 收稿日期:2021-07-29 接受日期:2021-08-26 出版日期:2021-11-28
  • 通信作者: Patrick Zardo

Non-intubated minimally-invasive lung surgery in Germany-current status and outlook

Patrick Zardo1(), Norman Zinne1, Alaa Selman1, Hayan Merhej1, Tobias Goecke1, Henning Starke2, Daniel Jaeger2, Jan Karsten2, Axel Haverich1   

  1. 1. Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
    2. Department of Anaesthesiology, Hannover Medical School, Hannover, Germany
  • Received:2021-07-29 Accepted:2021-08-26 Published:2021-11-28
  • Corresponding author: Patrick Zardo
  • About author:
    Contributions: (I) Conception and design: P Zardo, A Haverich; (II) Administrative support: H Starke, D Jaeger, J Karsten; (III) Provision of study materials or patients: All authors; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: None; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.
引用本文:

Patrick Zardo, Norman Zinne, Alaa Selman, Hayan Merhej, Tobias Goecke, Henning Starke, Daniel Jaeger, Jan Karsten, Axel Haverich. Non-intubated minimally-invasive lung surgery in Germany-current status and outlook[J]. 中华胸部外科电子杂志, 2021, 08(04): 205-208.

Patrick Zardo, Norman Zinne, Alaa Selman, Hayan Merhej, Tobias Goecke, Henning Starke, Daniel Jaeger, Jan Karsten, Axel Haverich. Non-intubated minimally-invasive lung surgery in Germany-current status and outlook[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2021, 08(04): 205-208.

Lung surgery under spontaneous ventilation (non-intubated video-assisted thoracoscopic surgery, niVATS) picked up a lot of momentum during the past few years. Surgeons and anesthetists alike want to forgo known risks of orotracheal intubation and mechanical ventilation, ranging from local complications, like mucosal injury or even deleterious tracheal laceration and rupture, to increased release of pro-inflammatory cytokines and diaphragmatic dysfunction secondary to muscle relaxation. Despite initial adoption of VATS in Germany having been slow due to a general reticence towards it in smaller units, major thoracic centers nowadays have well-established minimally invasive programs and even perform minor non-intubated procedures on a regular basis. Experience with major niVATS cases still is sparse across Western Europe, and limited to specialized and highly trained centers, where exceptionally complex and often multimorbid patients can safely undergo lung surgery under spontaneous ventilation. Our group pioneered niVATS lobectomy in Germany back in 2018, and since then we tried to spread the technique by means of multidisciplinary Masterclass-courses held at our center, in which the participant's initial reticence to perform niVATS often changed to enthusiasm for the procedure. This in turn led several visiting units to start with their own programs, and some of them even reported their initial experience. This article offers a short historic overview of VATS in general, gives an insight into how niVATS got pioneered in Germany and presents the current state of affairs.

Lung surgery under spontaneous ventilation (non-intubated video-assisted thoracoscopic surgery, niVATS) picked up a lot of momentum during the past few years. Surgeons and anesthetists alike want to forgo known risks of orotracheal intubation and mechanical ventilation, ranging from local complications, like mucosal injury or even deleterious tracheal laceration and rupture, to increased release of pro-inflammatory cytokines and diaphragmatic dysfunction secondary to muscle relaxation. Despite initial adoption of VATS in Germany having been slow due to a general reticence towards it in smaller units, major thoracic centers nowadays have well-established minimally invasive programs and even perform minor non-intubated procedures on a regular basis. Experience with major niVATS cases still is sparse across Western Europe, and limited to specialized and highly trained centers, where exceptionally complex and often multimorbid patients can safely undergo lung surgery under spontaneous ventilation. Our group pioneered niVATS lobectomy in Germany back in 2018, and since then we tried to spread the technique by means of multidisciplinary Masterclass-courses held at our center, in which the participant's initial reticence to perform niVATS often changed to enthusiasm for the procedure. This in turn led several visiting units to start with their own programs, and some of them even reported their initial experience. This article offers a short historic overview of VATS in general, gives an insight into how niVATS got pioneered in Germany and presents the current state of affairs.

1
O'Brien MF, Galvin DJ, Mulhall JP. The contribution of Irish urology to clinical practice. Urology 2009;74:972-8.
2
Jacobaeus H. Über die Möglichkeit die Zystoskopie bei Untersuchung seröser Höhlungen anzuwenden. Munch Med Wochenschr 1910;57:2.
3
Berci G. Professor Harold H. Hopkins. Surg Endosc 1995;9:667-8.
4
Berci G, Cuschieri A. Karl Storz, 1911-1996. A remembrance. Surg Endosc 1996;10:1123.
5
Semm K. Endoscopic appendectomy. Endoscopy 1983;15:59-64.
6
Roviaro G, Rebuffat C, Varoli F, et al. Videoendoscopic pulmonary lobectomy for cancer. Surg Laparosc Endosc 1992;2:244-7.
7
Tamburrini A, Mineo TC. A glimpse of history: non-intubated thoracic surgery. Video-assist Thorac Surg 2017;2:52
8
Vischnevski AA. Local anesthesia in thoracic surgery: lungs, heart and esophagus. Minerva Anestesiol 1954;20:432-5.
9
Wiedemann K, Fleischer E, Dressler P. Separation of the airways: historical aspects. Anasthesiol Intensivmed Notfallmed Schmerzther 2002;37:8-15.
10
Tschopp JM, Brutsche M, Frey JG. Treatment of complicated spontaneous pneumothorax by simple talc pleurodesis under thoracoscopy and local anaesthesia. Thorax 1997;52:329-32.
11
Nezu K, Kushibe K, Tojo T, et al. Thoracoscopic wedge resection of blebs under local anesthesia with sedation for treatment of a spontaneous pneumothorax. Chest 1997;111:230-5.
12
Al-Abdullatief M, Wahood A, Al-Shirawi N, et al. Awake anaesthesia for major thoracic surgical procedures: an observational study. Eur J Cardiothorac Surg 2007;32:346-50.
13
Chen JS, Cheng YJ, Hung MH, et al. Nonintubated thoracoscopic lobectomy for lung cancer. Ann Surg 2011;254:1038-43.
14
Chen KC, Cheng YJ, Hung MH, et al. Nonintubated thoracoscopic surgery using regional anesthesia and vagal block and targeted sedation. J Thorac Dis 2014;6:31-6.
15
Gonzalez-Rivas D, Fernandez R, de la Torre M, et al. Single-port thoracoscopic lobectomy in a nonintubated patient: the least invasive procedure for major lung resection? Interact Cardiovasc Thorac Surg 2014;19:552-5.
16
Witte B, Wolf M, Hillebrand H, et al. Complete video-assisted thoracoscopic surgery anatomic segmentectomy for clinical stage I lung carcinoma - technique and feasibility. Interact Cardiovasc Thorac Surg 2011;13:148-52.
17
Dienemann H, Hoffmann H. VATS lobectomy in stage I lung cancer: standard or experimental procedure. Zentralbl Chir 2012;137:228-33.
18
Ismail M, Helmig M, Swierzy M, et al. Uniportal VATS: the first German experience. J Thorac Dis 2014;6:S650-5.
19
Fitzmaurice BG, Brodsky JB. Airway rupture from double-lumen tubes. J Cardiothorac Vasc Anesth 1999;13:322-9.
20
Schilling T, Kozian A, Huth C, et al. The pulmonary immune effects of mechanical ventilation in patients undergoing thoracic surgery. Anesth Analg 2005;101:957-65, table of contents.
21
Murphy GS, Szokol JW, Avram MJ, et al. Postoperative residual neuromuscular blockade is associated with impaired clinical recovery. Anesth Analg 2013;117:133-41.
22
Wen Y, Liang H, Qiu G, et al. Non-intubated spontaneous ventilation in video-assisted thoracoscopic surgery: a meta-analysis. Eur J Cardiothorac Surg 2020;57:428-37.
23
Pompeo E, Mineo D, Rogliani P, et al. Feasibility and results of awake thoracoscopic resection of solitary pulmonary nodules. Ann Thorac Surg 2004;78:1761-8.
24
Tacconi F, Pompeo E, Fabbi E, et al. Awake video-assisted pleural decortication for empyema thoracis. Eur J Cardiothorac Surg 2010;37:594-601.
25
Ambrogi V, Mineo TC. VATS biopsy for undetermined interstitial lung disease under non-general anesthesia: comparison between uniportal approach under intercostal block vs. three-ports in epidural anesthesia. J Thorac Dis 2014;6:888-95.
26
Wang ML, How CH, Hung MH, et al. Long-term outcomes after nonintubated versus intubated thoracoscopic lobectomy for clinical stage I non-small cell lung cancer: A propensity-matched analysis. J Formos Med Assoc 2021. [Epub ahead of print]. doi: 10.1016/j.jfma.2021.04.018.
27
Zardo P, Zinne N, Logemann F, et al. Non-intubated uniportal video-assisted thoracoscopic surgery-lobectomy in Germany--the first 2 cases. J Vis Surg 2018;4:178.
28
Zinne N, Kropivnitskaya I, Selman A, et al. Minimal-invasive anatomische Lungenresektionen unter Spontanatmung. 2019. Z Herz-Thorax- Gefäßchir 33: 20.
29
Galetin T, Lopez-Pastorini A, Kosse N, et al. Video-assisted Thoracoscopic Surgery in Local Anaesthesia and Analgosedation- a Survey of the Members of the German Society of Thoracic Surgeons. Zentralbl Chir 2020;145:278-83.
30
Schieren M, Defosse J. To tube or not to tube: a skeptic's guide to nonintubated thoracic surgery. Curr Opin Anaesthesiol 2021;34:1-6.
31
Metelmann I, Broschewitz J, Pietsch UC, et al. Procedural times in early non-intubated VATS program - a propensity score analysis. BMC Anesthesiol 2021;21:44.
32
Gonzalez-Rivas D, Bonome C, Fieira E, et al. Non-intubated video-assisted thoracoscopic lung resections: the future of thoracic surgery? Eur J Cardiothorac Surg 2016;49:721-31.
33
Starke H, Zinne N, Leffler A, et al. Developing a minimally-invasive anaesthesiological approach to non-intubated uniportal video-assisted thoracoscopic surgery in minor and major thoracic surgery. J Thorac Dis 2020;12:7202-17.
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