| 1 |
Sung H，Ferlay J，Siegel RL，et al．Global Cancer Statistics 2020：GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries[J]．CA Cancer J Clin，2021，71（3）：209-249．
|
| 2 |
Travis WD，Brambilla E，Nicholson AG，et al．The 2015 World Health Organization Classification of Lung Tumors：Impact of Genetic，Clinical and Radiologic Advances Since the 2004 Classification[J]．J Thorac Oncol，2015，10（9）：1243-1260．
|
| 3 |
Giraud P，Antoine M，Larrouy A，et al．Evaluation of microscopic tumor extension in non-small-cell lung cancer for three-dimensional conformal radiotherapy planning[J]．Int J Radiat Oncol Biol Phys，2000，48（4）：1015-1024．
|
| 4 |
Onozato ML，Kovach AE，Yeap BY，et al．Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis[J]．Am J Surg Pathol，2013，37（2）：287-294．
|
| 5 |
Kadota K，Nitadori JI，Sima CS，et al．Tumor Spread through Air Spaces is an Important Pattern of Invasion and Impacts the Frequency and Location of Recurrences after Limited Resection for Small Stage I Lung Adenocarcinomas[J]．J Thorac Oncol，2015，10（5）：806-814．
|
| 6 |
Lewis CE，Pollard JW．Distinct role of macrophages in different tumor microenvironments[J]．Cancer Res，2006，66（2）：605-612．
|
| 7 |
Yoshida C，Kadota K，Ikeda T，et al．Tumor-associated macrophage infiltration is associated with a higher rate of tumor spread through air spaces in resected lung adenocarcinomas[J]．Lung Cancer，2021，158：91-96．
|
| 8 |
Yoshida C，Kadota K，Yamada K，et al．Tumor-associated CD163（+） macrophage as a predictor of tumor spread through air spaces and with CD25（+） lymphocyte as a prognostic factor in resected stage I lung adenocarcinoma[J]．Lung Cancer，2022，167：34-40．
|
| 9 |
Dongre A，Weinberg RA．New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer[J]．Nat Rev Mol Cell Biol，2019，20（2）：69-84．
|
| 10 |
Jung W，Chung JH，Yum S，et al．The differential prognostic impact of spread through air spaces in early-stage lung adenocarcinoma after lobectomy according to the pT descriptor[J]．J Thorac Cardiovasc Surg，2022，163（1）：277-284．
|
| 11 |
Shiono S，Yanagawa N．Spread through air spaces is a predictive factor of recurrence and a prognostic factor in stage I lung adenocarcinoma[J]．Interact Cardiovasc Thorac Surg，2016，23（4）：567-572．
|
| 12 |
Lee JS，Kim EK，Kim M，et al．Genetic and clinicopathologic characteristics of lung adenocarcinoma with tumor spread through air spaces[J]．Lung Cancer，2018，123：121-126．
|
| 13 |
Hu SY，Hsieh MS，Hsu HH，et al．Correlation of tumor spread through air spaces and clinicopathological characteristics in surgically resected lung adenocarcinomas[J]．Lung Cancer，2018，126：189-193．
|
| 14 |
Thunnissen E，Blaauwgeers HJ，de Cuba EM，et al．Ex Vivo Artifacts and Histopathologic Pitfalls in the Lung[J]．Arch Pathol Lab Med，2016，140（3）：212-220．
|
| 15 |
Song T，Jiang L，Zhuo Z，et al．Impacts of thoracoscopic surgery and high grade histologic subtypes on spread through air spaces in small stage I lung adenocarcinomas[J]．J Cancer Res Clin Oncol，2019，145（9）：2375-2382．
|
| 16 |
Metovic J，Falco EC，Vissio E，et al．Gross Specimen Handling Procedures Do Not Impact the Occurrence of Spread Through Air Spaces（STAS） in Lung Cancer[J]．Am J Surg Pathol，2021，45（2）：215-222．
|
| 17 |
Gross DJ，Hsieh MS，Li Y，et al．Spread Through Air Spaces （STAS） in Non-Small Cell Lung Carcinoma：Evidence Supportive of an In Vivo Phenomenon[J]．Am J Surg Pathol，2021，45（11）：1509-1515．
|
| 18 |
Eguchi T，Kameda K，Lu S，et al．Lobectomy Is Associated with Better Outcomes than Sublobar Resection in Spread through Air Spaces （STAS）-Positive T1 Lung Adenocarcinoma：A Propensity Score-Matched Analysis[J]．J Thorac Oncol，2019，14（1）：87-98．
|
| 19 |
Vaghjiani RG，Takahashi Y，Eguchi T，et al．Tumor Spread Through Air Spaces Is a Predictor of Occult Lymph Node Metastasis in Clinical Stage IA Lung Adenocarcinoma[J]．J Thorac Oncol，2020，15（5）：792-802．
|
| 20 |
Kadota K，Kushida Y，Katsuki N，et al．Tumor Spread Through Air Spaces Is an Independent Predictor of Recurrence-free Survival in Patients With Resected Lung Squamous Cell Carcinoma[J]．Am J Surg Pathol，2017，41（8）：1077-1086．
|
| 21 |
Mino-Kenudson M．Significance of tumor spread through air spaces （STAS） in lung cancer from the pathologist perspective[J]．Transl Lung Cancer Res，2020，9（3）：847-859．
|
| 22 |
Villalba JA，Shih AR，Sayo TMS，et al．Accuracy and Reproducibility of Intraoperative Assessment on Tumor Spread Through Air Spaces in Stage 1 Lung Adenocarcinomas[J]．J Thorac Oncol，2021，16（4）：619-629．
|
| 23 |
Yagi Y，Aly RG，Tabata K，et al．Three-Dimensional Histologic，Immunohistochemical，and Multiplex Immunofluorescence Analyses of Dynamic Vessel Co-Option of Spread Through Air Spaces in Lung Adenocarcinoma[J]．J Thorac Oncol，2020，15（4）：589-600．
|
| 24 |
Bains S，Eguchi T，Warth A，et al．Procedure-Specific Risk Prediction for Recurrence in Patients Undergoing Lobectomy or Sublobar Resection for Small （≤2 cm） Lung Adenocarcinoma：An International Cohort Analysis[J]．J Thorac Oncol，2019，14（1）：72-86．
|
| 25 |
Ren Y，Xie H，Dai C，et al．Prognostic Impact of Tumor Spread Through Air Spaces in Sublobar Resection for 1A Lung Adenocarcinoma Patients[J]．Ann Surg Oncol，2019，26（6）：1901-1908．
|
| 26 |
Kadota K，Kushida Y，Kagawa S，et al．Limited Resection Is Associated With a Higher Risk of Locoregional Recurrence than Lobectomy in Stage I Lung Adenocarcinoma With Tumor Spread Through Air Spaces[J]．Am J Surg Pathol，2019，43（8）：1033-1041．
|
| 27 |
Shiono S，Endo M，Suzuki K，et al．Spread Through Air Spaces Is a Prognostic Factor in Sublobar Resection of Non-Small Cell Lung Cancer[J]．Ann Thorac Surg，2018，106（2）：354-360．
|
| 28 |
Uruga H，Fujii T，Fujimori S，et al．Semiquantitative Assessment of Tumor Spread through Air Spaces （STAS） in Early-Stage Lung Adenocarcinomas[J]．J Thorac Oncol，2017，12（7）：1046-1051．
|
| 29 |
Han YB，Kim H，Mino-Kenudson M，et al．Tumor spread through air spaces （STAS）：prognostic significance of grading in non-small cell lung cancer[J]．Mod Pathol，2021，34（3）：549-561．
|
| 30 |
Saji H，Okada M，Tsuboi M，et al．Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer （JCOG0802/WJOG4607L）：a multicentre，open-label，phase 3，randomised，controlled，non-inferiority trial[J]．Lancet，2022，399（10335）：1607-1617．
|
| 31 |
Ding Y，Chen Y，Wen H，et al．Pretreatment prediction of tumour spread through air spaces in clinical stage I non-small-cell lung cancer[J]．Eur J Cardiothorac Surg，2022，62（3）：ezac248．
|
| 32 |
Kadota K，Kushida Y，Katsuki N，et al．Tumor Spread Through Air Spaces Is an Independent Predictor of Recurrence-free Survival in Patients With Resected Lung Squamous Cell Carcinoma[J]．Am J Surg Pathol，2017，41（8）：1077-1086．
|
| 33 |
Warth A，Muley T，Kossakowski CA，et al．Prognostic Impact of Intra-alveolar Tumor Spread in Pulmonary Adenocarcinoma[J]．Am J Surg Pathol，2015，39（6）：793-801．
|