总结接受胸膜可见肿瘤切除联合胸腔温热灌注化疗（HITHOC）的胸腺肿瘤患者的临床护理经验，为临床同类患者的围手术期护理提供针对性参考。

采用临床回顾性研究方法，纳入2024年1至5月在上海市胸科医院接受HITHOC的胸腺肿瘤伴胸膜转移患者20例。温热灌注化疗在胸膜剥脱术中或术后48 h内完成。对患者实施针对性全流程围手术期综合护理，包括术前评估准备、术中术后精准监测、呼吸道精细化管理、静脉水化专科护理、疼痛阶梯化护理、心理个性化支持等，以确保患者顺利康复。

20例患者均未出现术后肺不张、水电解质紊乱、体温及呼吸功能异常、置管时间延长等护理操作直接相关的并发症；2例出现术后漏气，1例出现阵发性房颤，1例在术后1个月出现肾损伤，对症处理后情况改善；20例患者术后住院（9.3±3.2）天均获得临床症状缓解、达到出院指征后顺利出院。

胸腺肿瘤伴胸膜转移患者行HITHOC的临床观察与针对性护理非常重要，直接关系到患者术后康复进程。护理人员必须认真落实治疗期间的相关护理工作，以确保患者得到有效、全面的围手术期护理支持。

To summarize the clinical nursing experience of patients with thymic tumors and pleural metastasis who underwent pleural tumor resection combined with hyperthermic intrathoracic chemotherapy (HITHOC), so as to provide a reference for perioperative nursing of similar patients.

This study adopted a clinical retrospective study design and included 20 patients with thymic tumors complicated with pleural metastasis who received HITHOC at Shanghai Chest Hospital from January to May 2024. HITHOC was performed during or within 48 hours after pleural stripping surgery. Patients received comprehensive and targeted perioperative nursing care throughout the process, including preoperative assessment and preparation, intraoperative and postoperative precise monitoring, refined respiratory tract management, specialized intravenous hydration care, stepped pain care, personalized psychological support, etc., to ensure a smooth recovery.

None of the 20 patients experienced postoperative atelectasis, electrolyte imbalance, abnormal body temperature and respiratory function, or prolonged catheterization time directly related to nursing operations; 2 patients had postoperative air leakage, 1 patient had paroxysmal atrial fibrillation, and 1 patient developed a kidney injury a month after surgery, all of which improved after symptomatic treatment; all 20 patients were discharged smoothly after relief of clinical symptoms and meeting the discharge criteria with an average postoperative hospital stay of (9.3±3.2) days.

Clinical observation and targeted nursing care for patients with thymic tumor complicated with pleural metastasis undergoing HITHOC are crucial and directly related to the postoperative recovery process. Nursing staff must conscientiously implement the relevant specialized nursing practices during treatment to ensure that patients receive effective and comprehensive perioperative nursing support.