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中华胸部外科电子杂志 ›› 2023, Vol. 10 ›› Issue (04) : 247 -256. doi: 10.3877/cma.j.issn.2095-8773.2023.04.10

综述

肺移植供肺缺血再灌注损伤的机制及预防
李宁, 刘言, 林慧庆()   
  1. 430061 武汉,武汉大学人民医院胸外科
  • 收稿日期:2023-06-08 修回日期:2023-09-14 接受日期:2023-11-06 出版日期:2023-11-28
  • 通信作者: 林慧庆
  • 基金资助:
    国家自然科学基金(82170106,82102269)

Mechanism and prevention of ischemia-reperfusion injury of donor lung transplantation

Ning Li, Yan Liu, Huiqing Lin()   

  1. Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
  • Received:2023-06-08 Revised:2023-09-14 Accepted:2023-11-06 Published:2023-11-28
  • Corresponding author: Huiqing Lin
引用本文:

李宁, 刘言, 林慧庆. 肺移植供肺缺血再灌注损伤的机制及预防[J]. 中华胸部外科电子杂志, 2023, 10(04): 247-256.

Ning Li, Yan Liu, Huiqing Lin. Mechanism and prevention of ischemia-reperfusion injury of donor lung transplantation[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2023, 10(04): 247-256.

肺移植供肺缺血再灌注损伤(IRI)是导致肺移植失败的主要原因之一。本文通过回顾近年来肺移植术后供肺IRI的现状,归纳其病理生理机制,总结当前较为有效的治疗措施,就该临床难题的未来进展作简要综述。

Ischemia reperfusion injury (IRI) is one of the main causes of lung transplantation failure. In this review, we summarized the current status of IRI after lung transplantation in recent years, pathophysiological mechanisms, the current effective therapeutic measures, and the future progress of this clinical problem.

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