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中华胸部外科电子杂志 ›› 2015, Vol. 02 ›› Issue (02) : 94 -97. doi: 10.3877/cma.j.issn.2095-8773.2015.02.004

所属专题: 文献

综述

血液miRNA在肺癌诊断中作用的研究进展
丁琦晨1, 郑敏1,()   
  1. 1. 200050 上海交通大学医学院附属同仁医院胸外科
  • 收稿日期:2015-03-22 出版日期:2015-05-28
  • 通信作者: 郑敏
  • 基金资助:
    上海市科委医学引导项目(124119b1900)

Research progress of role of blood miRNA in diagnosis of lung cancer

Qichen Ding1, Min Zheng1,()   

  1. 1. Department of Thoracic Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200050 , China
  • Received:2015-03-22 Published:2015-05-28
  • Corresponding author: Min Zheng
  • About author:
    Corresponding author: Zheng Min, Email:
引用本文:

丁琦晨, 郑敏. 血液miRNA在肺癌诊断中作用的研究进展[J]. 中华胸部外科电子杂志, 2015, 02(02): 94-97.

Qichen Ding, Min Zheng. Research progress of role of blood miRNA in diagnosis of lung cancer[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2015, 02(02): 94-97.

微小核糖核酸(miRNA)是一类新近发现的非编码小RNA分子,参与人体一系列的生理和病理过程,miRNA的表达异常可起到癌基因或抑癌基因的作用,对肿瘤的发生、发展有着重要的作用。肺癌发病率高、预后较差,是危害人类健康的重要恶性肿瘤。近年的研究表明,血液miRNA参与肺癌的发生、发展及治疗等诸多过程。

Objective

MicroRNA (miRNA) is a newly discovered family of non-coding small RNAs, which are involved in a series of human physiological and pathological processes. The abnormal expression of miRNA may serve as oncogenes or tumor suppressor genes for tumor occurrence and development. Lung cancer has a high incidence and poor prognosis, which is an important cancer hazard to human health. Recent studies have revealed that blood miRNA may participate in the development and treatment of lung cancer.

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