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中华胸部外科电子杂志 ›› 2015, Vol. 02 ›› Issue (04) : 218 -221. doi: 10.3877/cma.j.issn.2095-8773.2015.04.002

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综述

胸段食管癌淋巴结清扫的研究进展
陈先凯1, 李印1,(), 孙海波1   
  1. 1. 450008 郑州大学附属肿瘤医院胸外科
  • 收稿日期:2015-04-18 出版日期:2015-11-28
  • 通信作者: 李印

Research progress of lymphadenectomy for thoracic esophageal cancer

Xiankai Chen1, Yin Li1,(), Haibo Sun1   

  1. 1. Department of Thoracic Surgery, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China
  • Received:2015-04-18 Published:2015-11-28
  • Corresponding author: Yin Li
  • About author:
    Corresponding author: Li Yin, Email
引用本文:

陈先凯, 李印, 孙海波. 胸段食管癌淋巴结清扫的研究进展[J/OL]. 中华胸部外科电子杂志, 2015, 02(04): 218-221.

Xiankai Chen, Yin Li, Haibo Sun. Research progress of lymphadenectomy for thoracic esophageal cancer[J/OL]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2015, 02(04): 218-221.

目前,有关胸段食管癌淋巴结清扫的最佳范围仍存在很多争议,尤其是在5年生存率及围手术期并发症发生率和病死率方面,三野淋巴结清扫是否优于二野淋巴结清扫。有证据表明在胸段食管癌治疗中三野淋巴结清扫较二野淋巴结清扫更能使患者受益,尤其是对于合并淋巴结转移的患者,但是尚缺乏大样本量随机对照研究的进一步证实。另外,挽救性颈部淋巴结清扫可能是治疗根治性食管癌术后颈部淋巴结复发患者的主要方法,但缺少相关的前瞻性研究。该文主要对胸段食管癌治疗中淋巴结最佳清扫范围及挽救性清扫在根治食管癌术后颈部淋巴结复发患者治疗中的意义进行讨论。

There have been many controversies about the optimal extent of lymphadenectomy for thoracic esophageal cancer, especially on whether three-field lymphadenectomy is superior to two-field lymphadenectomy with respect to the 5-year survival rate and perioperative morbidities and mortality. Published evidence indicated that three-field lymphadenectomy could be a priority for thoracic esophageal cancer, especially for tumors with lymph node metastasis. Given the lack of large-sample randomized controlled studies, further evaluations are necessary. Salvage cervical lymphadenectomy might be the main treatment for esophageal carcinoma patients who develop recurrence in the cervical lymph node after curative esophagectomy; however, more prospective studies are warranted in future. In this review, we focus on two aspects of controversy about the optimal extent of lymphadenectomy for thoracic esophageal cancer and significance of salvage cervical lymphadenectomy in the treatment of patients who develop recurrence in the cervical lymph node after curative esophagectomy.

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