To investigate the differences in lung cancer detection rates with low-dose spiral CT(LDCT) among people with different genders and ages in western Shandong and southern Hebei, and provide evidence for making better screening programs.

The clinical data of 2 056 cases undergoing lung cancer screening with LDCT in Liaocheng Second People’s Hospital in 2015 were retrospectively analyzed. Patients were divided into groups by gender, by age based on expert consensus of high-risk population of lung cancer and by age according to the actual findings of high-risk population of lung cancer, respectively, and the lung cancer detection rates were compared between groups, respectively.

Twenty-two of these 2 056 cases were confirmed as lung cancer, among whom 20 were adenocarcinoma and the other 2 were squamous cell carcinoma. Twenty-one(95.5%) cases with lung cancer aged between 45 and 75 years. The lung cancer detection rates of males and females were 0.8%(10/1 217) and 1.4%(12/839), respectively, and there was no significant difference between them(χ²=1.738, P=0.187). Based on expert consensus of high-risk population of lung cancer, the lung cancer detection rates of high-risk group(50-75 years old) and low-risk group(<50 years or >75 years) were 1.3%(15/1 158) and 0.8%(7/898), respectively, and there was no significant difference between them(χ²=1.271, P=0.26). According to the actual findings of high-risk population of lung cancer, the lung cancer detection rates of new high-risk group(45-75 years old) and new low-risk group(<45 years or >75 years) were 1.4%(21/1 502) and 0.2%(1/554), respectively, and there were significant differences between them (χ²=5.668, P=0.017).

Attention should be paid to lung cancer screening with LDCT both in males and females in western Shandong and southern Hebei, and the age of high-risk population of lung cancer is well to be defined as 45-75 years.