The 10-yeay experience of lung transplantation in Shanghai Chest Hospital

doi:10.3877/cma.j.issn.2095-8773.2017.04.06

Abstract

Abstract:

Objective

To share the experience of 10 years of perioperative management for lung transplantation.

Methods

A retrospective study of transplantation cases from Jan 2007 to Dec 2016 in Shanghai Chest hospital was conducted. There were 6 cases of single lung transplantation (2 cases of re-transplantation, 4 cases of lobe transplantation) and 24 cases of double lung transplantation. There were 14 cases of IPF, 8 cases of COPD, 3 cases of bronchiectasis, 2 cases of BOS , 1 case of bronchoalveolar carcinoma, 1 case of LAM and 1 case of immotile cilia syndrome. The cumulative survival rate and the major causes of death after 1, 3 and 5 years after operation were analyzed.

Results

30-day mortality was 6.7%(2/30). Circulatory and cardiac failure were the main causes. 90-day mortality was 13.3% (4/30). Stroke and massive airway bleeding were another two causes. 1, 3 and 5-year survival rates were 60%, 50%, 41% respectively. Pneumonia and anastomosis complications were the main causes of death in the first 3 years after transplantation. BOS was the main cause of death after the first 3 years of transplantation.

Conclusions

Lung transplantation was an effective treatment method in treating various end stage benign lung diseases.

Key words: Lung transplantation, Complication, Overall survival, End stage benign lung diseases

Xufeng Pan, Shijie Fu, Jun Yang, Kejian Cao, Heng Zhao. The 10-yeay experience of lung transplantation in Shanghai Chest Hospital[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2017, 04(04): 224-227.

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References 10

1	Trulock EP, Edwards LB, Taylor DO, et al. Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult lung and heart-lung transplant report--2005[J]. J Heart Lung Transplant, 2005, 24(8): 956-967.
2	Hadjiliadis D, Angel LF. Controversies in lung transplantation: are two lungs better than one? [J] Semin Respir Crit Care Med, 2006, 27(5): 561-566.
3	Schaffer JM, Singh SK, Reitz BA, et al. Single- vs double-lung transplantation in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis since the implementation of lung allocation based on medical need[J]. JAMA, 2015, 313(9): 936-948.
4	Borro JM, Delgado M, Coll E, et al. Single-lung transplantation in emphysema: Retrospective study analyzing survival and waiting list mortality[J]. World J Transplant, 2016, 6(2): 347-355.
5	Neurohr C, Huppmann P, Thum D，et al. Potential functional and survival benefit of double over single lung transplantation for selected patients with idiopathic pulmonary fibrosis[J]. Transpl Int, 2010, 23(9):887-896.
6	Yusen RD, Edwards LB, Kucheryavaya AY, et al. The registry of the International Society for Heart and Lung Transplantation: thirty-first adult lung and heart-lung transplant report--2014; focus theme: retransplantation[J]. J Heart Lung Transplant, 2014, 33(10): 1009-1024.
7	Novick RJ, Sch？fers HJ, Stitt L, et al. Recurrence of obliterative bronchiolitis and determinants of outcome in 139 pulmonary retransplant recipients[J]. J Thorac Cardiovasc Surg, 1995, 110(5): 1402-1413; discussion 1413-1414.
8	Strueber M, Fischer S, Gottlieb J, et al. Long-term outcome after pulmonary retransplantation[J]. J Thorac Cardiovasc Surg, 2006, 132(2): 407-412.
9	Novick RJ, Stitt LW, Al-Kattan K, et al. Pulmonary retrans-plantation: predictors of graft function and survival in 230 patients. Pulmonary Retransplant Registry[J]. Ann Thorac Surg, 1998. 65(1): 227-234.
10	Verleden SE, Sacreas A, Vos R, et al. Advances in understanding bronchiolitis obliterans after lung transplantation[J]. Chest, 2016，150(1): 219-225.

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