Application and prospect of medical robot in diagnosis and treatment of small pulmonary nodule

doi:10.3877/cma.j.issn.2095-8773.2022.01.05

Abstract

Abstract:

Rapid progress has been seen in the minimally invasive diagnosis and treatment of pulmonary nodule in recent years; both interventional robotic bronchoscope and surgical robot system are constantly updated and improved to meet clinical needs, which bring medical benefits to doctors and patients. However, the popularity of medical robots, especially robotic bronchoscope and domestic surgical robot, remains low. Robotic bronchoscope including Monarch^TM and Ion^TM, which were approved by the United States Food and Drug Administration in 2018 and 2019 respectively, is characterized with precise motion, high flexibility and strong stability, and can realize the navigation and biopsy of bronchus below grade 8. The biopsy rate, diagnosis rate and complication result of robotic bronchoscope are better than that of traditional bronchoscope. The widely used surgical robot system, Da Vinci system, is applied in all areas of thoracic surgery, including lung, esophagus, and mediastinum. Domestic surgical robot system has been approved for application, and the domestic robotic bronchoscope is also on the way. There is a great prospective for the application of medical robots and the development of domestic equipment.

Key words: Robotic bronchoscope, Surgical robot, Pulmonary nodule

Chao Guo, Jiaqi Zhang, Zhen Li, Guibin Bian, Shanqing Li. Application and prospect of medical robot in diagnosis and treatment of small pulmonary nodule[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2022, 09(01): 35-40.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhxbwkdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-8773.2022.01.05

https://zhxbwkdzzz.cma-cmc.com.cn/EN/Y2022/V09/I01/35

References 32

1	Siegel RL, Miller KD, Fuchs HE，et al．Cancer Statistics, 2021[J]．CA Cancer J Clin，2021，71(1): 7-33.
2	Sung H, Ferlay J, Siegel RL，et al．Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries[J]．CA Cancer J Clin，2021，71(3): 209-249.
3	Kian W, Zemel M, Levitas D，et al．Lung cancer screening: a critical appraisal[J]．Curr Opin Oncol，2022，34(1): 36-43.
4	Walter K．Pulmonary Nodules[J]．JAMA，2021，326(15): 1544.
5	Shen YC, Chen CH, Tu C．Advances in Diagnostic Bronchoscopy[J]．Diagnostics (Basel)，2021，11(11): 1984.
6	Chen AC, Gillespie CT．Robotic Endoscopic Airway Challenge: REACH Assessment[J]．Ann Thorac Surg，2018，106(1): 293-297.
7	Rojas-Solano JR, Ugalde-Gamboa L, Machuzak M．Robotic Bronchoscopy for Diagnosis of Suspected Lung Cancer: A Feasibility Study[J]．J Bronchology Interv Pulmonol，2018，25(3): 168-175.
8	Yarmus L, Akulian J, Wahidi M，et al．A Prospective Randomized Comparative Study of Three Guided Bronchoscopic Approaches for Investigating Pulmonary Nodules: The PRECISION-1 Study[J]．Chest，2020，157(3): 694-701.
9	Fielding D, Bashirzadeh F, Son JH，et al．First Human Use of a New Robotic-Assisted Fiber Optic Sensing Navigation System for Small Peripheral Pulmonary Nodules[J]．Respiration，2019，98(2): 142-150.
10	钟长镐，周子青，马家骏，等．机器人支气管镜系统对比格犬肺外周预置弹簧圈定位及移除的有效性和安全性初步探究[J]．中华结核和呼吸杂志，2021，44(12): 1071-1077.
11	肺小结节术前辅助定位技术专家共识(2019版)．专家组肺小结节术前辅助定位技术专家共识(2019版)[J]．中国胸心血管外科临床杂志，2019，26(2): 109-113.
12	Chang JY, Mehran RJ, Feng L，et al．Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery[J]．Lancet Oncol，2021，22(10): 1448-1457.
13	Non-Small Cell Lung Cancer. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Version 1. 2022[EB/OL]．[2022-01-01]． URL
14	Kwoh YS, Hou J, Jonckheere EA，et al．A robot with improved absolute positioning accuracy for CT guided stereotactic brain surgery[J]．IEEE Trans Biomed Eng，1988，35(2): 153-160.
15	Leal Ghezzi T, Campos Corleta O．30 Years of Robotic Surgery[J]．World J Surg，2016，40(10): 2550-2557.
16	Kappert U, Schneider J, Cichon R，et al．Closed chest totally endoscopic coronary artery bypass surgery: fantasy or reality?[J]．Curr Cardiol Rep，2000，2(6): 558-563.
17	Soliman BG, Nguyen DT, Chan EY，et al．Impact of da Vinci Xi robot in pulmonary resection[J]．J Thorac Dis，2020，12(7): 3561-3572.
18	Nakauchi M, Uyama I, Suda K，et al．Robot-assisted mediastinoscopic esophagectomy for esophageal cancer: the first clinical series[J]．Esophagus，2019，16(1): 85-92.
19	Chen K, Zhang X, Jin R，et al．Robot-assisted thoracoscopic surgery for mediastinal masses: a single-institution experience[J]．J Thorac Dis，2020，12(2): 105-113.
20	Gharagozloo F, Atiquzzaman N, Meyer M，et al．Robotic first rib resection for thoracic outlet syndrome[J]．J Thorac Dis，2021，13(10): 6141-6154.
21	Qiu T, Zhao Y, Xuan Y，et al．Robotic-assisted double-sleeve lobectomy[J]．J Thorac Dis，2017，9(1): E21-E25.
22	Yang HX, Woo KM, Sima CS，et al．Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer: Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy[J]．Ann Surg，2017，265(2): 431-437.
23	Kneuertz PJ, D’Souza DM, Richardson M，et al．Long-Term Oncologic Outcomes After Robotic Lobectomy for Early-stage Non-Small-cell Lung Cancer Versus Video-assisted Thoracoscopic and Open Thoracotomy Approach[J]．Clin Lung Cancer，2020，21(3): 214-224.
24	柴新春，许世广，刘博，等．ⅠA期非小细胞肺癌行达芬奇机器人和电视胸腔镜肺段切除术近期疗效对比分析[J]．中华胸心血管外科杂志，2021，37(11): 644-648.
25	Khandalavala K, Shimon T, Flores L，et al．Emerging surgical robotic technology: a progression toward microbots[J]．Ann Laparosc Endosc Surg，2020，5: 3.
26	微创®图迈®腔镜手术机器人在上海市胸科医院顺利举行了多学科、多中心临床试验启动仪式[Z]．[2021-11-19]． URL
27	国产微创®图迈®腔镜手术机器人完成多学科、多中心注册临床试验手术病例[Z]．2022-01-22． URL
28	易波，蒋娟，宋智，等．国产妙手S手术机器人首次临床应用经验[J]．中华普通外科杂志，2016，31(6): 512-513.
29	Taurchini M, Quarato CMI, Frongillo EM，et al．Intraoperative Lung Ultrasound (ILU) for the Assessment of Pulmonary Nodules[J]．Diagnostics (Basel)，2021，11(9): 1691.
30	Zhou Z, Wang Z, Zheng Z，et al．An "alternative finger" in robotic-assisted thoracic surgery: intraoperative ultrasound localization of pulmonary nodules[J]．Med Ultrason，2017，19(4): 374-379.
31	Gangadharan S, Sarkaria IN, Rice D，et al．Multiinstitutional Phase 2 Clinical Trial of Intraoperative Molecular Imaging of Lung Cancer[J]．Ann Thorac Surg，2021，112(4): 1150-1159.
32	Predina JD, Newton AD, Keating J，et al．A Phase I Clinical Trial of Targeted Intraoperative Molecular Imaging for Pulmonary Adenocarcinomas[J]．Ann Thorac Surg，2018，105(3): 901-908.

[1]	Jingxin Chen, Mei Li, Jieya Chen. Risk factors related to pulmonary infection after thoracoscopic pulmonary nodules [J]. Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition), 2023, 17(04): 238-243.
[2]	Li Jiang, Xiaohui Wang, Weiyi Li, Shuangyun Gou, Min Ding, Li Yang. Influence of innovative intelligent health education and follow-up management on anxiety of patients with pulmonary nodules: a randomized control trial [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(04): 485-489.
[3]	Huajuan Li, Yingjun Tang, Saini Wang, Wang Xu, Ling Lin, Xi Li, Huaping Huang. Analysis of clinical and CT features of the patients with pulmonary nodules and establishment of prediction model to evaluate the probability of malignancy in pulmonary nodules [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(03): 318-323.
[4]	Ji Chen, Caixia Deng, Houli Zhang, Bingjing Zhu, Pan Liu, Jian He, Chunlan Tang, Xiangdong Zhou, Hu Luo. Study on the cognitive and anxiety status of patients with high-risk pulmonary nodules [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2023, 16(02): 164-168.
[5]	Yufang Chen, Kang Wang, Wenhao Wu, Houli Zhang, Xiangdong Zhou. Prognostic analysis of adjuvant targeted therapy for EGFR-positive ⅠA stage invasive lung adenocarcinoma after complete resection [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2022, 15(06): 776-781.
[6]	Houli Zhang, Hu Luo, Kang Wang, Yufang Chen, Xinglin Yi, Xiangdong Zhou. Construction of a predictive model of benign and malignant pulmonary nodules Using dual-energy CT and the clinical value of quantitative parameters of iodine map [J]. Chinese Journal of Lung Diseases(Electronic Edition), 2022, 15(05): 630-636.
[7]	Zhipeng Zhao, Yongfu Ma, Changjiang Feng, Meng Zhang, Yang Liu. A single-center retrospective analysis of a surgical strategy based on pulmonary sub-segments [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2023, 16(02): 85-90.
[8]	Mengchan Su, Ying Zheng, Qiao Wang, Yu Chen, Maojun Li, Fan Yang. Robotic single-port hysterectomy using the Edge Medical SP1000 surgical system: a novel technique to avoid auxiliary port [J]. Chinese Journal of Laparoscopic Surgery(Electronic Edition), 2022, 15(05): 307-310.
[9]	Zheng Dai, Jiahao Dai, Xiangnan Yu, Zheng Wang, Guobin Wang. Progress in colorectal minimally invasive surgical procedures, equipments and strategies [J]. Chinese Journal of Colorectal Diseases(Electronic Edition), 2023, 12(02): 158-162.
[10]	Wei Cao, Dahai Zhao, Xudong Zhao. Value of serum miR-146b-3p, miR-15b-5p, and miR-16-5p in differential diagnosis and prognosis evaluation of benign and malignant pulmonary nodules [J]. Chinese Journal of Clinicians(Electronic Edition), 2022, 16(06): 529-535.
[11]	Yufei Fu, Yayong Huang, Tao Wang, Wei Cao. Application comparison of CT-guided pulmonary nodule positioning needle and micro-coil positioning before solitary pulmonary nodule thoracoscopic resection [J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2022, 10(03): 272-277.
[12]	Fenjian Lao, Wei Wang, Guiyan Tan, Chengzhi Zhou, Mengzhang He. Clinical features of patients with pulmonary nodules and their significance in judging benign and malignant [J]. Chinese Journal of Clinical Laboratory Management(Electronic Edition), 2022, 10(03): 147-152.
[13]	Jiawei Chen, Rui Wang, Jiaxi He, Shuben Li. Application the integrated operating room on localization and resection of pulmonary nodule: a systematic review [J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2022, 09(02): 80-85.
[14]	Han Tang, Qun Wang, Lijie Tan, Di Ge, Yunfeng Yuan. Overview of pulmonary nodules positioning methods [J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2022, 09(02): 100-103.
[15]	Qingdao Zhang, Hualong Wang. Identification value of MRI apparent diffusion coefficient and voxel incoheren motion parameters for pulmonary nodules in middle-and-old age patients [J]. Chinese Journal of Geriatrics Research(Electronic Edition), 2023, 10(01): 26-29.

Please choose a citation manager

Content to export