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Chinese Journal of Thoracic Surgery(Electronic Edition) ›› 2023, Vol. 10 ›› Issue (02): 126-130. doi: 10.3877/cma.j.issn.2095-8773.2023.02.10

• Review • Previous Articles    

Research progress of spread through air space on lung adenocarcinoma

Xiao Chen, Changqing Liu, Hangcheng Zhou, Tian Li, Xiaohui Sun, Mingsheng Wu, Liangdong Xu, Meiqing Xu, Mingran Xie()   

  1. Department of Thoracic Surgery, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei 230001, China
    Department of Pathology, The First Affiliated Hospital of USTC, Division of Life Science and Medicine, University of Science and Technology of China, Hefei 230001, China
  • Received:2023-01-13 Revised:2023-03-17 Accepted:2023-05-16 Online:2023-05-28 Published:2023-06-30
  • Contact: Mingran Xie

Abstract:

The World Health Organization (WHO) recognized spread through air space (STAS) as a new invasive form of lung cancer in 2015. STAS has a close relationship with tumor histology, clinical stage, lymphatic invasion, and vascular invasion as a risk factor for poor patient prognosis. STAS research has crucial implications for patients with lung adenocarcinoma’s long-term prognosis. This page discusses STAS’s definition, potential mechanisms, association with various pathological forms of lung cancer, surgical procedures, prognosis, and current disputes.

Key words: Lung adenocarcinoma, Spread through air space, Surgery, Prognosis

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