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Chinese Journal of Thoracic Surgery(Electronic Edition) ›› 2023, Vol. 10 ›› Issue (04): 247-256. doi: 10.3877/cma.j.issn.2095-8773.2023.04.10

• Review • Previous Articles    

Mechanism and prevention of ischemia-reperfusion injury of donor lung transplantation

Ning Li, Yan Liu, Huiqing Lin()   

  1. Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China
  • Received:2023-06-08 Revised:2023-09-14 Accepted:2023-11-06 Online:2023-11-28 Published:2023-12-21
  • Contact: Huiqing Lin

Abstract:

Ischemia reperfusion injury (IRI) is one of the main causes of lung transplantation failure. In this review, we summarized the current status of IRI after lung transplantation in recent years, pathophysiological mechanisms, the current effective therapeutic measures, and the future progress of this clinical problem.

Key words: Lung transplantation, Donor lung, Ischemia reperfusion injury, Mechanism, Prevention

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