Clinical research of stomach tube width and gastroesophageal reflux after esophagectomy for esophageal cancer

doi:10.3877/cma.j.issn.2095-8773.2016.01.025

Abstract

Abstract:

Objective

To summarize the conditions of reflux after esophagectomy for esophageal cancer using stomach tube, and investigate the influence of stomach tube width on reflux after esophagectomy for esophageal cancer.

Methods

According to the order of admission, 60 patientsundergoing esophagectomy for esophageal cancer using stomach tube were randomly divided into group A (stomach tube width ≥ 3 cm, 30 cases) and group B (stomach tube width <3 cm, 30 cases). Eleven to fourteen days after recovery of intestinal function, 24 h esophageal pH monitoring was conducted.

Results

The times of reflux, times of reflux >5 min, time of pH<4.00 and longest reflux time in group A were significantly larger or longer than those in group B(t=2.735, P=0.012; t=4.502, P=0.001; t=3.435, P=0.023; t=4.286, P=0.002).

Conclusions

Stomach tube width may influence the occurrence of reflux, and thin stomachtube can reduce the reflux after esophagectomy for esophageal cancer.

Key words: Gastroesophageal reflux, Esophageal cancer, pH monitoring, Stomach tube

Qingtong Shi, Huangxin Fan, Yali Diao. Clinical research of stomach tube width and gastroesophageal reflux after esophagectomy for esophageal cancer[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2016, 03(01): 25-28.

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References 12

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指标		A组(n＝30)	B组(n＝30)	χ²/t值	P值
年龄(＋s，岁)		57.5±8.3	58.2±8.4	－0.063	0.375
性别(例)		?	?	0.003	0.680
?	男性	18	17	?	?
?	女性	12	13	?	?
病灶位置(例)		?	?	0.066	0.502
?	上段	5	4	?	?
?	中段	15	16	?	?
?	下段	10	10	?	?
病理类型(例)		?	?	0.045	0.683
?	溃疡型	15	14	?	?
?	蕈伞型	6	7	?	?
?	髓质型	4	5	?	?
?	缩窄型	5	4	?	?
肿瘤分期(例)		?	?	χ²＝0.039	0.715
?	Ⅰ期	8	6	?	?
?	Ⅱ期	19	20	?	?
?	Ⅲ期	3	4	?	?

指标		A组(n＝30)	B组(n＝30)	χ²/t值	P值
年龄(＋s，岁)		57.5±8.3	58.2±8.4	－0.063	0.375
性别(例)		?	?	0.003	0.680
?	男性	18	17	?	?
?	女性	12	13	?	?
病灶位置(例)		?	?	0.066	0.502
?	上段	5	4	?	?
?	中段	15	16	?	?
?	下段	10	10	?	?
病理类型(例)		?	?	0.045	0.683
?	溃疡型	15	14	?	?
?	蕈伞型	6	7	?	?
?	髓质型	4	5	?	?
?	缩窄型	5	4	?	?
肿瘤分期(例)		?	?	χ²＝0.039	0.715
?	Ⅰ期	8	6	?	?
?	Ⅱ期	19	20	?	?
?	Ⅲ期	3	4	?	?

组别	例数	反流次数	反流超过5 min的次数	最长反流时间(min)	pH值<4.00的总时间( min)
A组^①	30	18. 37±7. 28	12.03±7.56	104.55±74. 64	163.55±20.76
B组^②	30	14. 05±6. 03	7.25±3.38	85.38±55.50	145.31±16.58
健康对照组^[2]^③	20	11. 15±6. 67	0.65±0.59	4.50±2.93	140.12±13.35
①③比较	?	t＝5.821	t＝15.410	t＝18.525	t＝6.917
?	?	P＝0.000	P＝0.000	P＝0.000	P＝0.006
②③比较	?	t＝3.628	t＝8.763	t＝12.951	t＝2.246
?	?	P＝0.003	P＝0.000	P＝0.000	P＝0.018
①②比较	?	t＝2.735	t＝4.502	t＝4.286	t＝3.435
?	?	P＝0.012	P＝0.001	P＝0.002	P＝0.023

组别	例数	反流次数	反流超过5 min的次数	最长反流时间(min)	pH值<4.00的总时间( min)
A组^①	30	18. 37±7. 28	12.03±7.56	104.55±74. 64	163.55±20.76
B组^②	30	14. 05±6. 03	7.25±3.38	85.38±55.50	145.31±16.58
健康对照组^[2]^③	20	11. 15±6. 67	0.65±0.59	4.50±2.93	140.12±13.35
①③比较	?	t＝5.821	t＝15.410	t＝18.525	t＝6.917
?	?	P＝0.000	P＝0.000	P＝0.000	P＝0.006
②③比较	?	t＝3.628	t＝8.763	t＝12.951	t＝2.246
?	?	P＝0.003	P＝0.000	P＝0.000	P＝0.018
①②比较	?	t＝2.735	t＝4.502	t＝4.286	t＝3.435
?	?	P＝0.012	P＝0.001	P＝0.002	P＝0.023

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