Effect of nasal feeding fluid on postoperative nutritional status and gastrointestinal tolerance in patients with esophageal cancer

doi:10.3877/cma.j.issn.2095-8773.2017.02.04

Abstract

Abstract:

Objective

To study the effect of the nasal fluids assisted enteral nutrition on Gastrointestinal tolerability and nutritional status of esophageal perioperative patients.

Methods

According to random number table, 90 patients with esophageal surgery were divided into research group (n=45) and control group (n=45). The study group was provided with enteral nutrition emulsion, while nasal fluids. The control group was only provided with enteral nutrition emulsion.The trial period was 7 days.The basic demographic data and clinical information, metabolic markers of Hepatic function and nutrition metabolism were observed.

Results

On the 7^th day after surgery, the level of tumor nutrition risk in the study group was higher than that in the control group (P<0.05). The comparison of gastrointestinal tolerability, the anal exhaust time was earlier than the control group; the difference incidence of diarrhea and distention of the study group and the control group patients were significant (P<0.05). However, the incidence of nausea and vomiting in the two groups was not statistically significant (P>0.05).

Conclusions

Enteral nutrition auxiliary nasogastric liquid is able to improve the nutritional status of the patients and the gastrointestinal tolerance is good.It is a safe and effective treatment.

Key words: Esophageal, Nasal fluids, Gastrointestinal tolerance: Enteral nutrition, Perioperation

Qingtong Shi, Yali Diao, Guanghuai Yao. Effect of nasal feeding fluid on postoperative nutritional status and gastrointestinal tolerance in patients with esophageal cancer[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2017, 04(02): 87-91.

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References 15

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项目		研究组(45例)	对照组(45例)	检验值	P值
年龄(岁，±s)		56.5±7.3	57.2±7.6	t＝－0.062	0.325
性别[例(%)]		?	?	χ²＝0.003	0.672
?	男性	29(64.4)	28(62.2)	?	?
?	女性	16(35.6)	17(37.8)	?	?
肿瘤部位[例(%)]		?	?	χ²＝0.031	0.532
?	上段	8(17.8)	7(15.6)	?	?
?	中段	24(53.3)	23(51.1)	?	?
?	下段	13(28.9)	15(33.3)	?	?
肿瘤分期[例(%)]		?	?	χ²＝0.059	0.790
?	Ⅰ期	12(26.7)	11(24.4)	?	?
?	Ⅱ期	25(55.6)	26(57.8)	?	?
?	Ⅲ期	8(17.8)	8(17.8)	?	?
体重(kg，±s)		49.7±8.3	51.2±9.2	t＝0.035	0.485
BMI(kg/m²，±s)		22.1±1.6	21.8±1.4	t＝0.062	0.813
术后EN时间(h，±s)		28.5±4.2	29.1±3.9	t＝0.047	0.765

项目		研究组(45例)	对照组(45例)	检验值	P值
年龄(岁，±s)		56.5±7.3	57.2±7.6	t＝－0.062	0.325
性别[例(%)]		?	?	χ²＝0.003	0.672
?	男性	29(64.4)	28(62.2)	?	?
?	女性	16(35.6)	17(37.8)	?	?
肿瘤部位[例(%)]		?	?	χ²＝0.031	0.532
?	上段	8(17.8)	7(15.6)	?	?
?	中段	24(53.3)	23(51.1)	?	?
?	下段	13(28.9)	15(33.3)	?	?
肿瘤分期[例(%)]		?	?	χ²＝0.059	0.790
?	Ⅰ期	12(26.7)	11(24.4)	?	?
?	Ⅱ期	25(55.6)	26(57.8)	?	?
?	Ⅲ期	8(17.8)	8(17.8)	?	?
体重(kg，±s)		49.7±8.3	51.2±9.2	t＝0.035	0.485
BMI(kg/m²，±s)		22.1±1.6	21.8±1.4	t＝0.062	0.813
术后EN时间(h，±s)		28.5±4.2	29.1±3.9	t＝0.047	0.765

检测指标		研究组(45例)	对照组(45例)	t值	P值
白蛋白(g/L)		?	?	?	?
?	术前	36.6±6.3	37.1±7.9	0.054	0.632
?	术后第7天	32.8±5.1	28.9±4.8	4.583	0.031
前白蛋白(mg/L)		?	?	?	?
?	术前	208.6±14.1	210.4±15.5	0.067	0.783
?	术后第7天	180.7±11.4	163.6±12.2	5.150	0.028
乳酸脱氢酶(IU/L)		?	?	?	?
?	术前	179.6±12.3	180.5±12.1	0.085	0.921
?	术后第7天	135.5±11.3	106.5±10.9	5.063	0.023
尿素(mmol/L)		?	?	?	?
?	术前	5.7±1.5	5.6±1.5	0.068	0.776
?	术后第7天	4.9±1.5	4.4±1.4	6.642.	0.017
总胆固醇(mmol/L)		?	?	?	?
?	术前	4.7±0.5	4.8±0.4	0.078	0.835
?	术后第7天	4.4±0.4	4.0±0.4	6.191	0.020
血红蛋白(g/L)		?	?	?	?
?	术前	118.4±10.6	118.4±10.5	0.081	0.956
?	术后第7天	109.5±10.9	101.4±10.8	7.053	0.011

检测指标		研究组(45例)	对照组(45例)	t值	P值
白蛋白(g/L)		?	?	?	?
?	术前	36.6±6.3	37.1±7.9	0.054	0.632
?	术后第7天	32.8±5.1	28.9±4.8	4.583	0.031
前白蛋白(mg/L)		?	?	?	?
?	术前	208.6±14.1	210.4±15.5	0.067	0.783
?	术后第7天	180.7±11.4	163.6±12.2	5.150	0.028
乳酸脱氢酶(IU/L)		?	?	?	?
?	术前	179.6±12.3	180.5±12.1	0.085	0.921
?	术后第7天	135.5±11.3	106.5±10.9	5.063	0.023
尿素(mmol/L)		?	?	?	?
?	术前	5.7±1.5	5.6±1.5	0.068	0.776
?	术后第7天	4.9±1.5	4.4±1.4	6.642.	0.017
总胆固醇(mmol/L)		?	?	?	?
?	术前	4.7±0.5	4.8±0.4	0.078	0.835
?	术后第7天	4.4±0.4	4.0±0.4	6.191	0.020
血红蛋白(g/L)		?	?	?	?
?	术前	118.4±10.6	118.4±10.5	0.081	0.956
?	术后第7天	109.5±10.9	101.4±10.8	7.053	0.011

组别	总例数	腹胀	腹泻(≥3次)	恶心	呕吐	肛门排气开始时间(h)
研究组	45	3(6.7)	3(6.7)	2(4.4)	1(2.2)	38.5±3.2
对照组	45	8(17.8)	6(13.3)	3(6.7)	1(2.2)	45.1±4.9
检验值	?	χ²＝3.853	χ²＝2.275	χ²＝1.016	χ²＝0.787	t＝2.665
P值	?	0.028	0.036	0.169	0.435	0.037

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