To compare and evaluate the clinical effect of multi-channel single-hole laparoscopic puncture device in da-Vinci robot-assisted thoracoscopic extended thymectomy, and to discuss its application advantages.

We performed a retrospective review of 45 myasthenia gravies patients who had da-Vinci robot-assisted thoracoscopic extended thymectomy at the Jiangxi Province General Hospital between June 2021 and February 2025. Patients were divided into experimental groups and control group according to surgical approaches. There were 23 patients in the experimental group (using the multi-channel single-hole laparoscopic puncture device duration operation), and the other 22 patients who used the normal robotic endoscopic cannula were treated as the control group. The basic operation conditions and postoperative recovery data were observed and compared.

All the 45 patients successfully completed the surgery and recovered, with no case changed to thoracotomy. There were no statistically significant differences in preoperative clinical data. Compared the experimental group with the control group, the differences in the operation duration [ (158.26±60.51) min vs (207.27±84.07) min], the number of lymph nodes removed during surgery was [ (7.30±5.63) vs (1.91±3.85) ], value of CO₂ by postoperative artery blood gas analysis [ (38.66±5.09) mmol/L vs (42.69±5.39) mmol/L] were statistically significant (P<0.05). There were no statistically significant differences between the two groups in terms of intraoperation bleeding volume, postoperative 24 h chest drainage volume, indwelling time of the thoracic drainage tube, and duration of anodyne use.

Using multi-channel single-hole laparoscopic puncture device in da-Vinci robot-assisted thoracoscopic extended thymectomy can better expose the surgical field, thereby shortening the surgical time. In addition, this application can increase the extent of clearing mediastinum adipose tissue, especially around the deep cervical area, and reduce the postoperative CO₂ retention, without increasing the duration of postoperative pain. The application is simple to handle and inexpensive, which is worth promoting.