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Chinese Journal of Thoracic Surgery(Electronic Edition) ›› 2024, Vol. 11 ›› Issue (02): 79-84. doi: 10.3877/cma.j.issn.2095-8773.2024.02.01

• Guidelines and Consensus •    

Interpretation of the surgical section of the 2024 first edition of the National Comprehensive Cancer Network (NCCN) guidelines for non-small cell lung cancer

Kuan Xu1, Heng Zhao1, Bo Ye1,()   

  1. 1. Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China
  • Received:2024-01-11 Revised:2024-03-02 Accepted:2024-04-08 Online:2024-05-28 Published:2024-06-27
  • Contact: Bo Ye

Abstract:

Non-small cell lung cancer (NSCLC) represents a prevalent malignant neoplasm, with surgical resection serving as its primary therapeutic modality. Following a pivotal randomized trial released by the North American Lung Cancer Study Group in 1995, which demonstrated a heightened local recurrence rate and diminished survival in T1N0 stage lung cancer patients undergoing segmentectomy compared to lobectomy, the latter has since been acknowledged as the established surgical approach for achieving curative outcomes in early-stage NSCLC. Nevertheless, during the latter part of the 20th century, segmentectomy, renowned for its optimization of lung function preservation, progressively gained traction in the landscape of lung cancer treatment. Furthermore, the exploration of thoracoscopic techniques and robot-assisted surgery has emerged as a focal point in research. Substantial advancements have been witnessed in the realm of surgical treatment for NSCLC in recent years. This article endeavors to expound upon the surgical section of the 2024 first edition of the National Comprehensive Cancer Network (NCCN) guidelines for NSCLC, offering intricate elucidations pertaining to surgical indications, methodologies, lymph node dissection strategies, etc. Its overarching objective is to facilitate a nuanced comprehension among surgeons regarding the underlying principles and methodologies governing NSCLC surgical interventions.

Key words: Non-small cell lung cancer, National Comprehensive Cancer Network guidelines, Interpretation of guidelines

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