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Chinese Journal of Thoracic Surgery(Electronic Edition) ›› 2018, Vol. 05 ›› Issue (04): 239-242. doi: 10.3877/cma.j.issn.2095-8773.2018.04.08

Special Issue:

• Review • Previous Articles     Next Articles

Recent research advances in the mechanism of contraction and diastolic regulation of human lower esophageal sphincter

Ke Zhang1,(), Jinwei Xue2, Junling Huang3, Jie Liu4, Haibin Liu5, Lianlian Song6   

  1. 1. Department of Thoracic Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei Province 071000
    2. Department of Orthopeadic Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei Province 071000
    3. Department of Thoracic Surgery, Hospital of Lixian County, Baoding, Hebei Province 071400
    4. Department of Neurosurgery, Hospital of Lixian County, Baoding, Hebei Province 071400
    5. Department of General Surgery, The People’s Hospital of Qingyuan District of Baoding City, Hebei Province 071100
    6. Department of Operation Room, Hospital of Lixian County, Baoding, Hebei Province 071400
  • Received:2018-08-25 Online:2018-11-28 Published:2018-11-28
  • Contact: Ke Zhang
  • About author:
    Corresponding author: Zhang Ke, Email:

Abstract:

Human lower esophageal sphincter (LES) is regulated by neuroregulation, self-regulation and humoral regulation. Although neuroregulation is accomplished by a variety of different neurotransmitters, it is ultimately accomplished by the myenteric plexus that controls the self-regulation mechanism. Humoral regulation involves a variety of hormone substances, and the main hormone substances have different regulatory functions due to different ligands and receptors. The regulatory mechanism of some hormones on human LES needs further study.

Key words: Lower esophageal sphincter, Human, Neuroregulation, Self-regulation, Humoral regulation

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