Research progress of benign pulmonary nodules

doi:10.3877/cma.j.issn.2095-8773.2020.01.009

Abstract

Abstract:

In recent years, pulmonary nodules emerge in large numbers and gradually become the focus of thoracic surgery. A significant proportion of surgically removed lung nodules are benign pulmonary nodules.The imaging manifestations of some benign nodules are similar to those of malignant ones, which are easy to be misdiagnosed. This article outlines the clinical characteristics of benign pulmonary nodules, including imaging, pathology, and other aspects, with the aim of promoting awareness of benign pulmonary nodules.

Key words: Pulmonary nodules, Benign, Image, Pathology, Operation

Wenjun Cao, Hongsheng Xue, Jianyang Xu, Zhilong Zhao. Research progress of benign pulmonary nodules[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2020, 07(01): 51-55.

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References 41

[1]	中华医学会呼吸病学分会肺癌学组，中国肺癌防治联盟专家组．肺结节诊治中国专家共识(2018年版)[J]．中华结核和呼吸杂志，2018，41(10)：763-771.
[2]	Patel V K, Naik S K, Naidich D P, et al. A practical algorithmic approach to the diagnosis and management of solitary pulmonary nodules: part 1: radiologic characteristics and imaging modalities[J]. Chest, 2013, 143(3): 825-839.
[3]	Kikano G E, Fabien A, Schilz R. Evaluation of the solitary pulmonary nodule[J]. Am Fam Physician, 2015，92(12)：1084-1091.
[4]	Brandman S, Ko J P. Pulmonary nodule detection, characterization, and management with multidetector computed tomography[J]. J Thorac Imaging, 2011, 26(2)：90-105.
[5]	陈其瑞，刘艳，司丽芳，等.173例术前CT疑诊为恶性肿瘤的肺良性病变特征分析[J]．中国胸心血管外科临床杂志，2018，25(11)：21-27.
[6]	Snoeckx A, Dendooven A, Carp L, et al. Wolf in sheep’s clothing: Primary lung cancer mimicking benign entities[J]. Lung Cancer, 2017, 112：109-117.
[7]	Ohshimo S, Guzman J, Costabel U, et al. Differential diagnosis of granulomatous lung disease: clues and pitfalls[J]. Eur Respir Rev, 2017, 26(145). pii: 170012.
[8]	Mukhopadhyay S, Farver C F, Vaszar L T, et al. Causes of pulmonary granulomas: a retrospective study of 500 cases from seven countries[J]. J Clin Pathol, 2012，65(1)：51-57.
[9]	Sakakibara Y, Suzuki Y, Fujie T, et al. Radiopathological features and identification of mycobacterial infections in granulomatous nodules resected from the lung[J]. Respiration, 2017, 93(4)：264-270.
[10]	Patterson K C, Chen E S. The pathogenesis of pulmonary sarcoidosis and implications for treatent.[J] Chest, 2018, 153(6)：1432-1442.
[11]	中华医学会呼吸病学分会间质性肺疾病学组，中国医师协会呼吸医师分会间质性肺疾病工作委员会．中国肺结节病诊断和治疗专家共识[J]．中华结核和呼吸杂志，2019, 42(9)：685-693.
[12]	Culver D A, Judson M A. New advances in the management of pulmonary sarcoidosis[J]. BMJ, 2019，367：l5553.
[13]	Nemec S F, Bankier A A, Eisenberg R L. Upper lobe-predominant diseases of the lung[J]. AJR Am J Roentgenol, 2013，200(3)：W222-W237.
[14]	Sim Y T, Goh Y G, Dempsey M F, et al. PET-CT evaluation of solitary pulmonary nodules: correlation with maximum standardized uptake value and pathology[J]. Lung, 2013, 191(6)：625-632.
[15]	Porvaznik I, Solovic I, Mokry J. Non-tuberculous mycobacteria: classification, diagnostics, and therapy[J]. Adv Exp Med Biol, 2017，944：19-25.
[16]	Kaplan J E, Benson C, Holmes K K, et al. Guidelines for the prevention and treatment of opportunistic infections in HIV-infected adults and adolescents: recommendations from CDC, the National Institut Es of Health, and the HIV Medicine Association of the Infectious Diseases Society of America[J]. MMWR Recomm Rep, 2009, 58 (RR-4): 1- 207.
[17]	诸绍锋，卢增新，王亚琴，等. CT在诊断与鉴别肺部真菌感染中的临床价值分析[J]．中华医院感染学杂志，2016，26(18)：4141-4143.
[18]	Suzuki M, Araki K, Matsubayashi S, et al. A case of recurrent hemoptysis caused by pulmonary actinomycosis diagnosed using transbronchial lung biopsy after bronchial artery embolism and a brief review of the literature[J]. Ann Transl Med, 2019，7(5)：108.
[19]	Kim S R, Jung L Y, Oh I J, et al. Pulmonary actinomycosis during the first decade of 21st century: Cases of 94 patients[J]. BMC Infect Dis, 2013，13：216.
[20]	中国医药教育协会感染疾病专业委员会．感染相关生物标志物临床意义解读专家共识[J]．中华结核和呼吸杂志，2017，40(4)：243-257.
[21]	Hou X, Kou L, Han X, et al. Pulmonary cryptococcosis characteristics in immunocompetent patients—A twenty year clinical retrospective analysis in China[J]. Mycoses, 2019, 62(10)：937-944.
[22]	Wang D, Wu C, Gao J, et al. Comparative study of primary pulmonary cryptococcosis with multiple nodules or masses by CT and pathology[J]. Exp Ther Med, 2018，16(6)：4437-4444.
[23]	Leiter Herrán F, Restrepo C S, Alvarez Gómez D I, et al. Hamartomas from head to toe: an imaging overview[J]. Br J Radiol, 2017，90(1071)：20160607.
[24]	Saadi M M, Barakeh D H, Husain S, et al. Large multicystic pulmonary chondroid hamartoma in a child presenting as pneumothorax[J]. Saudi Med J, 2015，36(4)：487-489.
[25]	Kishore M, Gupta P, Preeti, et al. Pulmonary hamartoma mimicking malignancy: A cytopathological diagnosis[J]. J Clin Diagn Res, 2016，10(11)：ED06-ED07.
[26]	Cruickshank A, Stieler G, Ameer F. Evaluation of the solitary pulmonary nodule[J]. Intern Med J, 2019, 49(3)：306-315.
[27]	吴光耀，唐丽萍，朱瑞萍，等. 肺内淋巴结的CT表现特点及与病理对照[J]. 中华放射学杂志，2018，52(7)：513-517.
[28]	Davison A G, Heard B E, Mcallister W A, et al. Cryptogenic organizing pneumonitis[J]. Q J Med, 1983, 52(207)：382-394.
[29]	Zare Mehrjardi M, Kahkouee S, Pourabdollah M. Radio-pathological correlation of organising pneumonia (OP): A pictorial review[J]. Br J Radiol，2017, 90(1071)：20160723.
[30]	魏淑珍，朱思红，李素娟，等．隐源性机化性肺炎及继发性机化性肺炎的临床特征及影像特点分析[J]．国际呼吸杂志，2018，38(3)：192-196.
[31]	Khan M, Faisal A, Ibrahim H, et al. Pulmonary benign metastasizing leiomyoma: A case report[J]. Respir Med Case Rep, 2018; 24: 117-121.
[32]	Kolaczyk K, Chamier-Ciemińska K, Walecka A, et al. Pulmonary benign metastasizing leiomyoma from the uterine leiomyoma: a case report[J]. Pol J Radiol, 2015, 80: 107-110.
[33]	Kleinschmidt M C, Scherbaum C W, Müller T. Inflammatory pseudotumour of the lung as a rare differential diagnosis of a pulmonary mass - a case report and overview of the literature[J]. Pneumologie, 2010, 64(4)：246-248.
[34]	Degheili J A, Kanj N A, Koubaissi S A, et al. Indolent lung opacity: Ten years follow-up of pulmonary inflammatory pseudo-tumor[J]. World J Clin Cases, 2017，5(2)：61-66.
[35]	Travis W D, Brambilla E, Nicholson A G, et al. The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification[J]. J Thorac Oncol, 2015，10(9)：1243-1260.
[36]	Zhou L, Sun C, Huang Y, et al. Pulmonary sclerosing hemangioma with a rare symptom: A case report and review of the literature[J]. Mol Clin Oncol, 2017 Feb；6(2)：221-224.
[37]	Devouassoux-Shisheboran M, Hayashi T, Linnoila RI，et al. A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium[J]. Am J Surg Pathol, 2000, 24(7)：906-916.
[38]	Wang F L, Tan Y Y, Gu X M, et al. Comparison of positron emission tomography using 2-[18F]-fluoro-2-deoxy-D-glucose and 3-deoxy-3-[18F]-fluorothymidine in lung cancer imaging[J]. Chin Med J (Engl), 2016，129(24)：2926-2935.
[39]	Murrmann G B, van Vollenhoven FH, Moodley L. Aprrroach to a solid solitary pulmonary nodule in two different settings-" Common is common, rare is rare" [J]. J Thorac Dis, 2014，6(3)：237-248.
[40]	Wang X, Lv L, Zheng Q, et al. Differential diagnostic value of 64-slice spiral computed tomography in solitary pulmonary nodule[J]. Exp Ther Med, 2018，15(6)：4703-4708.
[41]	Hu H, Wang Q, Tang H, et al. Multi-slice computed tomography characteristics of solitary pulmonary ground-glass nodules: Differences between malignant and benign[J]. Thorac Cancer, 2016，7(1)：80-87.

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