The history, present and future of the NEOCRTEC5010 study

doi:10.3877/cma.j.issn.2095-8773.2020.04.06

Abstract

Abstract:

Esophagus cancer is one of the most common cancers in China, for which surgery is among the main treatment options. However, the overall survival of patients with locally advanced esophagus carcinoma receiving surgery alone are barely satisfactory. It therefore follows that in-depth studies concerning the efficacy of combined modality therapy for locally advanced esophagus carcinoma have been carried out. Recently, breakthroughs have been achieved in neoadjuvant chemoradiotherapy (NCRT), one of which is the NEOCRTEC5010 study by Sun Yat-sen University Cancer Center. The research indicated the dominant first-line position of NCRT plus surgery for locally advanced esophagus squamous cell carcinoma (ESCC) and caused widespread concern. The review aims to outline the history, present and future of the NEOCRTEC5010 study.

Key words: Esophageal squamous cell carcinoma, Neoadjuvant chemoradiotherapy, Combined modality therapy

Hong Yang, Caiyan Fang. The history, present and future of the NEOCRTEC5010 study[J]. Chinese Journal of Thoracic Surgery(Electronic Edition), 2020, 07(04): 233-239.

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